28 Days Later
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A highly contagious, aggression-inducing virus called "Rage" is unleashed in Great Britain after an infected chimpanzee is freed from a laboratory in Cambridge by a group of animal liberation activists. It spreads rapidly and becomes an epidemic, resulting in societal collapse. 28 days after the initial outbreak, bicycle courier Jim awakens from a coma in St Thomas' Hospital in London, which has been deserted with signs of catastrophe. Jim is attacked by infected humans, but rescued by survivors Selena and Mark. At Jim's request, the group travels to his parents' house in Deptford, where he learns that they died by suicide. That night, Mark gets a cut on his arm which is hit with infected blood during an attack, prompting Selena to kill him before he turns.
Another 28 days later, Jim recovers at a remote cottage in Cumbria, where the infected are shown dying of starvation. As a Finnish fighter jet flies overhead, Jim, Selena, and Hannah unfurl a huge cloth banner spelling the word "HELLO". The three survivors optimistically watch the jet as the pilot spots them.
Twenty-eight days after a killer virus was accidentally unleashed from a British research facility, a small group of London survivors are caught in a desperate struggle to protect themselves from the infected. Carried by animals and humans, the virus turns those it infects into homicidal maniacs -- and it's absolutely impossible to contain.
Twenty-eight days later, a man named Jim wakes up from a coma in an empty hospital. He ventures through the hospital, finding it deserted and rife with signs of chaos and unable to find anyone else there. Jim then leaves the hospital and heads out into Central London, finding the city is completely devoid of human life and rife with signs of a massive catastrophe - including a discarded newspaper that indicates Britain has endured a mass exodus, and a huge bulletin board covered with thousands of missing persons notices. Jim soon finds and enters a church which has been used as a mass grave and his filled with corpses. Jim finds people alive but odd-seeming in the church, including a priest who seems to be spasming and unintelligent and tries to attack Jim. Jim flees the church into the streets of London, with the raging people giving hot pursuit, when two survivors in gear rescue Jim by molotoving his pursuers and blowing up a nearby gas station.
Another twenty-eight days later, a bandaged Jim wakes up in recovery again, this time in bed in a remote cottage in Cumbria where Hannah and Selena have taken refuge and made home. Downstairs, Jim finds Selena sewing large swaths of fabric to make letters for spelling out a message, when Hannah alerts them that a European surveillance jet is coming. The trio rush outside and unfurl the last huge cloth banner, adding the final letter to the word "HELLO" laid out on the meadow. As an approaching Finnish military jet flies over the landscape towards their location, a pair of infected are shown lying helplessly in the road, dying of starvation, proving that just that part of Major West's "answer to infection" was correct. The jet flies over the three waving survivors and their giant message, and the radio of the jet can then be heard saying "Lähetätkö helikopterin? (Will you send a helicopter?)" as the jet flies off. Selena turns to Jim and wonders aloud, "Do you think he saw us this time?"
The Walking Dead's opening sees Deputy Rick Grimes on patrol with his partner, Shane, and taking an errant bullet from a gang of criminals. Rick falls into a coma and awakens some time later to find the hospital more or less abandoned. After working his way through empty corridors and discovering that most of the city has turned into zombies since he was last conscious, Rick meets Morgan and learns of the outbreak that has swept across the US, leaving a post-apocalyptic landscape behind. Many have pointed out the similarities between The Walking Dead and 28 Days Later's opening sequences, noting the coma and protagonist walking through an abandoned city concepts in particular.
Here, the authors used 2 distinct Th2-driven models of inflammation to determine the effects of eosinophils on lethal inoculation with a respiratory virus. The virus used in their study was pneumonia virus of mice (PVM), a mouse pathogen that is closely related to human RSV. Because human RSV is not a natural pathogen for mice, PVM can be considered a more appropriate alternative model of severe RSV infection in this species. The highly eosinophilic double transgenic eotaxin-2/IL-5 mouse strain,7 which possesses constitutively activated and degranulating eosinophils, showed a substantial twofold log reduction in virus recovery 4 days after PVM inoculation compared with the control strain. When the eosinophil-deficient ΔdblGATA strain was crossed with double transgenic eotaxin-2/IL-5 mice, creating a phenotype expressing high levels of eosinophil-specific cytokines but negligible numbers of eosinophils, virus recovery returned to baseline levels. Thus, decreased virus recovery was related to eosinophils alone and not the high cytokine levels present in the double transgenic eotaxin-2/IL-5 strain. These elegantly conducted experiments confirm earlier studies showing that eosinophils are important in respiratory virus clearance.
Those images tapped into a tradition that extends back to Gothic Victorian literature, notably Shelley and Stoker, who set their tales of murder and monsters in settings familiar to their readers, establishing Britain as the home of Gothic horror in the process. HG Wells followed suit with War of The Worlds (originally set in leafy Horsell Common) and later John Wyndham, the acclaimed science fiction novelist whose opening chapter of The Day of the Triffids, set in an deserted post-apocalyptic London overrun by man-eating plants, inspired Garland to write 28 Days Later.
A group of animal activists breaks into a lab in Cambridge, unwittingly setting free chimpanzees infected with an incurable "Rage Virus" that rapidly spreads across the country. Those infected lose their humanity and become lethally aggressive, and the epidemic causes societal collapse within a matter of weeks. Twenty-eight days after the initial outbreak, Jim (Cillian Murphy) wakes up from a coma and finds himself alone in a deserted hospital. In the Alex Garland penned and Boyle-directed feature, allegory and drama get wrapped up in Jim's perilous struggle to adapt to a new, post-apocalyptic world. 781b155fdc